Bergman, Lotta and Rosenholm, Jessica and Öst, Anna-Brita and Duchanoy, Alain and Kankaanpää, Pasi and Heino, Jyrki and Lindén, Mika. (2008) On the Complexity of Electrostatic Suspension Stabilization of Functionalized Silica Nanoparticles for Biotargeting and Imaging Applications. Journal of Nanomaterials, 2008. p. 1. ISSN 1687-4110Full text not available from this repository.
Different means of attaching streptavidin to surface functionalized silica particles with a diameter of 240 nm were investigated with special focus on suspension stability for electrostatically stabilized suspensions. The influence of two different fluorescent dyes covalently linked to the streptavidin on suspension stability was also studied. The results clearly show that the stability of the suspensions is crucially dependent on all functional groups present on the surface. The surface functions may either directly affect the effective surface charge if the functions contain charged groups, or indirectly by affecting the relative concentration of charged groups on the particle surface. Poly(ethylene imine)-functionalized silica particles, where the polymer is grown by surface hyperbranching polymerization, are shown to be promising candidates for bioapplications, as the zeta-potential can remain strongly positive even under biologically relevant conditions.
|Additional Information:||Copyright © 2008 Lotta Bergman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.|
|InterNano Taxonomy:||Nanomanufacturing Processes > Deposition of Nanostructured Films or Nanostructures > Surface polymerization
Nanomanufacturing Processes > Biological Techniques
Nanoscale Objects and Nanostructured Materials > Nanoparticles
|Collections:||Nanomanufacturing Research Collection|
|Depositing User:||Rebecca Reznik-Zellen|
|Date Deposited:||09 Nov 2009 15:05|
|Last Modified:||09 Nov 2009 15:05|
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