Chen, J. H. and Zhou, Y. L. and Wang, D. H. and He, F. and Rotello, V. M. and Carter, K. R. and Watkins, J. J. and Nugen, S. R.. (2015) UV-nanoimprint lithography as a tool to develop flexible microfluidic devices for electrochemical detection. Lab on a Chip, 15 (14). pp. 3086-3094.
Full text not available from this repository.Abstract
Research in microfluidic biosensors has led to dramatic improvements in sensitivities. Very few examples of these devices have been commercially successful, keeping this methodology out of the hands of potential users. In this study, we developed a method to fabricate a flexible microfluidic device containing electrowetting valves and electrochemical transduction. The device was designed to be amenable to a roll-to-roll manufacturing system, allowing a low manufacturing cost. Microchannels with high fidelity were structured on a PET film using UV-NanoImprint Lithography (UV-NIL). The electrodes were inkjet-printed and photonically sintered on second flexible PET film. The film containing electrodes was bonded directly to the channel-containing layer to form sealed fluidic device. Actuation of the multivalve system with food dye in PBS buffer was performed to demonstrate automated fluid delivery. The device was then used to detect Salmonella in a liquid sample.
| Item Type: | Article |
|---|---|
| Additional Information: | ISI Document Delivery No.: CL7UNTimes Cited: 0Cited Reference Count: 46Chen, Juhong Zhou, Yiliang Wang, Danhui He, Fei Rotello, Vincent M. Carter, Kenneth R. Watkins, James J. Nugen, Sam R.Center for Hierarchical Manufacturing, a National Science Foundation Nanoscale Science and Engineering Center at the University of Massachusetts under the NSF CMMI-1025020Support was provided by Center for Hierarchical Manufacturing, a National Science Foundation Nanoscale Science and Engineering Center at the University of Massachusetts supported under the NSF Award Number CMMI-1025020. The authors would also like to thank Brenda Warren in the Department of Polymer Science and Engineering at the University of Massachusetts, Amherst for her assistance with inkjet printing.0Royal soc chemistryCambridge1473-0189 |
| Uncontrolled Keywords: | Other Topics |
| Collections: | Nanomanufacturing Research Collection > Nanomanufacturing Nanoscale Science and Engineering Centers > Center for Hierarchical Manufacturing |
| Depositing User: | Robert Stevens |
| Date Deposited: | 12 Nov 2015 18:38 |
| Last Modified: | 12 Nov 2015 18:38 |
| URI: | http://eprints.internano.org/id/eprint/2334 |
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