Karnik, Rohit and Castelino, Kenneth and Majumdar, Arun. (2006) Field-effect control of protein transport in a nanofluidic transistor circuit. Applied Physics Letters, 88 (12). p. 123114. ISSN 00036951
Full text not available from this repository. (Request a copy)Abstract
Electrostatic interactions play an important role in nanofluidic channels when the channel size is comparable to the Debye screening length. Electrostatic fields have been used to control concentration and transport of ions in nanofluidic transistors. Here, we report a transistor-reservoir-transistor circuit that can be used to turn “on” or “off” protein transport using electrostatic fields with gate voltages of ±1 V. Our results suggest that global electrostatic interactions of the protein were dominant over other interactions in the nanofluidic transistor. The fabrication technique also demonstrates the feasibility of nanofluidic integrated circuits for the manipulation of biomolecules in picoliter volumes.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Nanofluidic channels |
| InterNano Taxonomy: | Nanoscale Objects and Nanostructured Materials > Nanodevice Structures > Nanoelectronic circuits and architectures Nanomanufacturing Processes > Biological Techniques |
| Collections: | Nanomanufacturing Research Collection > Nanomanufacturing Nanoscale Science and Engineering Centers > Center for Scalable and Integrated Nanomanufacturing |
| Depositing User: | Moureen Kemei |
| Date Deposited: | 24 Mar 2010 19:55 |
| Last Modified: | 30 Sep 2014 15:10 |
| URI: | http://eprints.internano.org/id/eprint/360 |
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