Field-effect control of protein transport in a nanofluidic transistor circuit

Karnik, Rohit and Castelino, Kenneth and Majumdar, Arun. (2006) Field-effect control of protein transport in a nanofluidic transistor circuit. Applied Physics Letters, 88 (12). p. 123114. ISSN 00036951

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Electrostatic interactions play an important role in nanofluidic channels when the channel size is comparable to the Debye screening length. Electrostatic fields have been used to control concentration and transport of ions in nanofluidic transistors. Here, we report a transistor-reservoir-transistor circuit that can be used to turn “on” or “off” protein transport using electrostatic fields with gate voltages of ±1 V. Our results suggest that global electrostatic interactions of the protein were dominant over other interactions in the nanofluidic transistor. The fabrication technique also demonstrates the feasibility of nanofluidic integrated circuits for the manipulation of biomolecules in picoliter volumes.

Item Type: Article
Uncontrolled Keywords: Nanofluidic channels
InterNano Taxonomy: Nanoscale Objects and Nanostructured Materials > Nanodevice Structures > Nanoelectronic circuits and architectures
Nanomanufacturing Processes > Biological Techniques
Collections: Nanomanufacturing Research Collection > Nanomanufacturing Nanoscale Science and Engineering Centers > Center for Scalable and Integrated Nanomanufacturing
Depositing User: Moureen Kemei
Date Deposited: 24 Mar 2010 19:55
Last Modified: 30 Sep 2014 15:10

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