Fung, Andrew O. and Kapadia, Vishal and Pierstorff, Erik and Ho, Dean and Chen, Yong. (2008) Induction of Cell Death by Magnetic Actuation of Nickel Nanowires Internalized by Fibroblasts. Journal of Physical Chemistry C, 112 (39). pp. 15085-15088. ISSN 1932-7447
Full text not available from this repository. (Request a copy)Abstract
Magnetic nanomaterials with multimodal functionalities have emerged as a versatile platform for biomedical applications that range from basic cellular interrogation to clinical nanomedicine. In this work, we have prepared electrodeposited ferromagnetic nickel nanowires for efficient internalization into 3T3 fibroblasts. Agitation of the nanowires by a low external field induced cell death, as assessed by MTT viability assays. The response of the interleukin-6 (IL-6) gene expression of the fibroblasts to nanowire-mediated cellular manipulation was examined by quantitative real-time polymerase chain reaction (qRT-PCR). These nanowires exhibited significant potential as therapeutic and interrogative platforms for biomedicine.
Item Type: | Article |
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Additional Information: | Reprinted with permission from "Induction of Cell Death by Magnetic Actuation of Nickel Nanowires Internalized by Fibroblasts", Fung A et al., J. Phys. Chem. C, 2008, 112 (39), pp 15085–15088. Copyright 2008 American Chemical Society |
Uncontrolled Keywords: | Nanomedicine |
InterNano Taxonomy: | Nanoscale Objects and Nanostructured Materials > Nanocomposites > Magnetic Nanoscale Objects and Nanostructured Materials > Nanowires |
Collections: | Nanomanufacturing Research Collection > Nanomanufacturing Nanoscale Science and Engineering Centers > Center for Scalable and Integrated Nanomanufacturing |
Depositing User: | Moureen Kemei |
Date Deposited: | 09 Apr 2010 14:28 |
Last Modified: | 26 Sep 2014 21:27 |
URI: | http://eprints.internano.org/id/eprint/417 |
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