Development of a Multi-Criteria Decision Analysis Tool to Support Selection of Nanomaterial Studies

Bruce, Gretchen M and Wetherington, Diane and Pleus, Richard C. (2010) Development of a Multi-Criteria Decision Analysis Tool to Support Selection of Nanomaterial Studies. In: Nanoinformatics 2010, November 3 - 5, 2010, Arlington, VA. (Unpublished)

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The database of information on nanomaterial toxicity studies is expanding rapidly and will continue, complicating the ability to identify and evaluate the quality of studies in the face of disparate data and to quickly identify those that will be most useful for furthering research. To assist researchers in identifying the "best" study or subset of studies based on a range of criteria, we are developing a multi-criteria decision analysis (MCDA)-based tool that will be incorporated into the collaborative Nanomaterial-Biological Interactions (NBI) knowledgebase currently being developed with researchers at Oregon State University (OSU). The tool will integrate with existing data repositories to identify studies that best meet criteria identified as important to stakeholders (researchers, policy makers, etc.), using a consistent, reproducible, and traceable method. Steps at the nascent stage of tool development include defining and characterizing the target user population and their priorities and objectives; characterizing information sources; establishing criteria that will be used to describe studies, which may include physical and chemical properties of the material, exposure and study characteristics, biological response measures, and indicators of study quality and reliability; and classifying studies according to these criteria. At each step in the process, we will obtain expert input from stakeholders. The tool, when complete, will prioritize information based on the extent to which it meets the criteria judged by the user to be most relevant and important.

Item Type: Conference or Workshop Item (Other)
Uncontrolled Keywords: nanomaterial studies, quality, Nanomaterial-Biological Interactions knowledgebase,
InterNano Taxonomy: Informatics and Standards
Tool development
Collections: National Nanomanufacturing Network Archive > Conferences and Workshops > Nanoinformatics 2010
Depositing User: Rebecca Reznik-Zellen
Date Deposited: 18 Mar 2011 19:18
Last Modified: 18 Mar 2011 19:18

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