Diffusion-Limited Patterning of Molecules in Nanofluidic Channels

Karnik, Rohit and Castelino, Kenneth and Duan, Chuanhua and Majumdar, Arun. (2006) Diffusion-Limited Patterning of Molecules in Nanofluidic Channels. Nano Letters, 6 (8). pp. 1735-1740. ISSN 1530-6984

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Abstract

Diffusion-limited patterning (DLP) is a new technique that enables patterning of labile molecular species in solution phase onto surfaces that are not easily accessible. This technique is self-aligning and is simple to implement for patterning multiple species. We demonstrated DLP by patterning alternating bands of fluorescently labeled and unlabeled streptavidin in biotin-functionalized nanofluidic channels with spatial resolution better than 1 μm. The methodology of DLP also enables experimental measurement of a unique parameter that relates molecular surface grafting density, concentration, diffusivity, and channel geometry.

Item Type: Article
Additional Information: Reprinted with permission from "Diffusion-Limited Patterning of Molecules in Nanofluidic Channels", Karnik R et al., Nano Lett., 6 (8), pp 1735–1740. Copyright 2006 American Chemical Society
InterNano Taxonomy: Nanoscale Objects and Nanostructured Materials > Other Nanostructured Materials > Self assembled monolayers
Nanomanufacturing Processes > Nanopatterning/Lithography
Collections: Nanomanufacturing Research Collection
Depositing User: Moureen Kemei
Date Deposited: 24 Mar 2010 22:37
Last Modified: 24 Mar 2010 22:37
URI: http://eprints.internano.org/id/eprint/369

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