Yum, Kyungsuk and Na, S. and Xiang, Y and Wang, N and Yu, MF. (2009) Mechanochemical Delivery and Dynamic Tracking of Fluorescent Quantum Dots in the Cytoplasm and Nucleus of Living Cells. Nano Letters, 9 (5). p. 2193. ISSN 15306984
Full text not available from this repository. (Request a copy)Abstract
Studying molecular dynamics inside living cells is a major but highly rewarding challenge in cell biology. We present a nanoscale mechanochemical method to deliver fluorescent quantum dots (QDs) into living cells, using a membrane-penetrating nanoneedle. We demonstrate the selective delivery of monodispersed QDs into the cytoplasm and the nucleus of living cells and the tracking of the delivered QDs inside the cells. The ability to deliver and track QDs may invite unconventional strategies for studying biological processes and biophysical properties in living cells with spatial and temporal precision, potentially with molecular resolution.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SIGNAL-TRANSDUCTION; REDOX STATE; LIVE CELLS; DIFFUSION; TRANSPORT; PROTEINS; SPECTROSCOPY; RECEPTORS; MOLECULES; MEMBRANE |
| InterNano Taxonomy: | Tool development |
| Collections: | Nanomanufacturing Research Collection |
| Depositing User: | Danielle Federa |
| Date Deposited: | 17 Jun 2009 14:54 |
| Last Modified: | 17 Jun 2009 14:54 |
| URI: | http://eprints.internano.org/id/eprint/133 |
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