Label Free DNA Detection Using Large Area Graphene Based Field Effect Transistor Biosensors

Guo, S. R. and Lin, J. and Penchev, M. and Yengel, E. and Ghazinejad, M. and Ozkan, C. S. and Ozkan, M.. (2011) Label Free DNA Detection Using Large Area Graphene Based Field Effect Transistor Biosensors. Journal of Nanoscience and Nanotechnology, 11 (6). pp. 5258-5263.

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Abstract

We describe the fabrication of highly sensitive graphene based field effect transistor (FET) biosensors with a cost-effective approach and their application in label-free Deoxyribonucleic acid (DNA) detection. Chemical vapor deposition (CVD) grown graphene layers were used to achieve mass production of FET devices via conventional photolithographic patterning. Non-covalent functionalization of the graphene layer with 1-Pyrenebutanoic acid succinimidyl ester ensures high conductivity and sensitivity of the FET device. The present device could reach a detection limit as low as 3 X 10(-9) M.

Item Type: Article
InterNano Taxonomy: Areas of Application > Medical and Pharmaceutical Industries
Nanoscale Objects and Nanostructured Materials > Other Nanostructured Materials > Graphene
Collections: Nanomanufacturing Research Collection > Nanomanufacturing Nanoscale Science and Engineering Centers > Center for Hierarchical Manufacturing
Depositing User: Robert Stevens
Date Deposited: 03 May 2012 16:57
Last Modified: 03 May 2012 16:57
URI: http://eprints.internano.org/id/eprint/1780

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