DNA-based Delivery Vehicles: pH-controlled Disassembly and Cargo Release

Keum, Jung-Won and Bermudez, Harry. (2012) DNA-based Delivery Vehicles: pH-controlled Disassembly and Cargo Release. Chemical Communications, 48 (99). pp. 12118-12120.

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Abstract

Non-Watson-Crick base pairing provides an in situ approach for actuation of DNA nanostructures through responses to solution conditions. Here we demonstrate this concept by using physiologically-relevant changes in pH to regulate DNA pyramid assembly/disassembly and to control the release of protein cargo.

Item Type: Article
Collections: Nanomanufacturing Research Collection > Nanomanufacturing Nanoscale Science and Engineering Centers > Center for Hierarchical Manufacturing
Depositing User: Robert Stevens
Date Deposited: 26 Mar 2014
Last Modified: 26 Mar 2014 19:43
URI: http://eprints.internano.org/id/eprint/2052

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