Protein coronas suppress the hemolytic activity of hydrophilic and hydrophobic nanoparticles

Saha, K. and Moyano, D. F. and Rotello, V. M.. (2014) Protein coronas suppress the hemolytic activity of hydrophilic and hydrophobic nanoparticles. Materials Horizons, 1 (1). pp. 102-105.

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Abstract

The role of nanoparticle surface hydrophobicity on hemolytic properties is established in the absence and presence of plasma proteins. Significantly, the formation of a plasma protein corona on the NP surface protects red blood cells from both hydrophilic and hydrophobic NP-mediated hemolysis.

Item Type: Article
Additional Information: ISI Document Delivery No.: AZ2NXTimes Cited: 4Cited Reference Count: 38Saha, Krishnendu Moyano, Daniel F. Rotello, Vincent M.National Institute of Health EB014277; NSF CMMI-1025020, DMR-0820506This research was supported in part by a grant from the National Institute of Health (grants EB014277). NSF support is acknowledged for NSEC Center for Hierarchical Manufacturing (CMMI-1025020, BY) and MRSEC facilities (DMR-0820506).Royal soc chemistryCambridge
Uncontrolled Keywords: size
Collections: Nanomanufacturing Research Collection > Nanomanufacturing Nanoscale Science and Engineering Centers > Center for Hierarchical Manufacturing
Depositing User: Robert Stevens
Date Deposited: 12 Nov 2015 18:38
Last Modified: 12 Nov 2015 18:38
URI: http://eprints.internano.org/id/eprint/2338

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